منابع مشابه
Pili in Gram - positive pathogens
| Most bacterial pathogens have long filamentous structures known as pili or fimbriae extending from their surface. These structures are often involved in the initial adhesion of the bacteria to host tissues during colonization. In Gram-negative bacteria, pili are typically formed by non-covalent interactions between pilin subunits. By contrast, the recently discovered pili in Gram-positive pat...
متن کاملType IV pili in Gram-positive bacteria.
Type IV pili (T4P) are surface-exposed fibers that mediate many functions in bacteria, including locomotion, adherence to host cells, DNA uptake (competence), and protein secretion and that can act as nanowires carrying electric current. T4P are composed of a polymerized protein, pilin, and their assembly apparatuses share protein homologs with type II secretion systems in eubacteria and the fl...
متن کاملAntibiotic Resistance, Part 1: Gram-positive Pathogens
The Jo 70 ABSTRACT Antibiotics have been instrumental in reducing mortality and morbidity associated with bacterial infections. However, antibiotic resistance has been increasing at an alarming rate due to overuse and inappropriate utilization. The emergence of resistance in Streptococcus pneumoniae, Staphylococcus aureus and enterococci is of concern. The increasing incidence of resistance in ...
متن کاملThe CodY pleiotropic repressor controls virulence in gram-positive pathogens.
CodY is involved in the adaptive response to starvation in at least 30 different low G+C gram-positive bacteria. After dimerization and activation by cofactor binding, CodY binds to a consensus palindromic DNA sequence, leading to the repression of approximately 5% of the genome. CodY represses the transcription of target genes when bound to DNA by competition with the RNA polymerase for promot...
متن کاملThe post-antibiotic effects of linezolid against Gram-positive pathogens.
OBJECTIVE To investigate the post-antibiotic effect (PAE) of linezolid against methicillin-resistant and -susceptible staphylococci, vancomycin-resistant and -susceptible enterococci. METHODS Clinical strains of Staphylococcus aureus (S. aureus), Staphylococcus epidermidis (S. epidermidis) and Enterococcus faecalis (E. faecalis) were isolated from hospitalized patients at Ege University Medic...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Reviews Microbiology
سال: 2006
ISSN: 1740-1526,1740-1534
DOI: 10.1038/nrmicro1443